Sherlock does not have living parents and TWO brothers.
There is NO hint of Holmes or Watson being gay.
Moriarty did NOT rise from the dead.
Moriarty was a calm, behind the scenes mastermind, who only appeared ONCE in the books.
Dr Watson did not marry an assassin.
Watson is told almost straight away by Holmes how he survived the Falls.
Apart from some obvious Conan Doyle themes, if all the character where given different names, then it would be unrecognizable.
The BBC is not producing Sherlock Holmes!